Shimadzu LCMS IT-TOF

Shimadzu LCMS IT-TOF

Location: College of Pharmacy, 550

  Unassisted Assisted
(1 hr)
UIC Cost $25 (per hour) $52 (per hour)
Other Academic $52 (per hour) $81 (per hour)
Non-Academic$104 (per hour) $162 (per hour)


The Shimadzu LCMS-IT-TOF is a hybrid mass spectrometer coupling atmospheric pressure ionization with Ion-Trap (IT) and Time-of-Flight (TOF) technologies. It delivers high mass accuracy and high mass resolution independent of MS mode.

Technical Specifications

Resolution is 10,000 at m/z 1000 independent of MS mode.

The LCMS-IT-TOF has been designed to maximize sensitivity and selectivity by optimizing the ion transport to the TOF analyzer and redefining the capability of the quadrupole ion trap. The ion trap is used to focus ions before ejection into the TOF as well as supporting MSn analysis with effective precursor ion selection capabilities (resolution > 1,000 at 1,000 m/z).

Compressed Ion Injection" (CII) (patented)
The CII method makes it possible to control the accumulation of ions before they are introduced into the ion trap. Adopted for the LCMS-IT-TOF, it effectively couples the LC system to the MS, dramatically increasing sensitivity.

Ballistic Ion Extraction (BIE) (patented)
The use of BIE accelerates ions into the TOF instantly, and combined with the Dual-Stage Reflectron (DSR) (patented), achieves faster, more stable, and higher resolution spectra.

Temperature Control of the Flight Tube
In concert with the localized ion due to BIE from the QIT and the 10bit high-speed transient recorder, the temperature control mechanism of the flight tube enables extended stability in mass accuracy.

High-speed Ion Polarity Switching
Utilizing a newly developed, accurate and stable power supply, in combination with an innovative high-voltage switch, allows for polarity switching in only 0.1 sec or less.