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The Mass Spectrometry Laboratory (MSL) serves as a campus-wide research core facility and resource for the analysis of a wide variety of molecules ranging from low molecular weight volatile compounds to high mass polymers and bio-polymers such as proteins. Types of measurements include qualitative and quantitative analysis, purity assessment, molecular weight determination, and high-resolution exact mass measurements for the determination of elemental compositions. The hyphenated techniques of gas chromatography mass spectrometry (GC-MS) and liquid chromatography mass spectrometry (LC-MS) permit the composition of complex mixtures to be analyzed, while tandem mass spectrometry (MS-MS) provides information regarding molecular structure. There are two laboratories, one in 550, College of Pharmacy Building, 833 South Wood Street, and the other in Room 109A, Science and Engineering South Building, 845 West Taylor Street. Currently eight instruments are in use: one single quadrupole LC-MS, two triple quadrupole LC-MS's, one quadrupole ion trap LC-MS, one high resolution magnetic sector tandem GC-MS, one high resolution qa-TOF tandem LC-MS, one high resolution MALDI/TOF, and one high resolution hybrid linear ion trap Fourier Transform ICR LC-MS. |